Friday, June 03, 2005

THE SYNTHESIS OF NITROBENZENE

THE SYNTHESIS OF NITROBENZENE THROUGH ELECTROPHILIC SUBSTIUTION.

One of the concepts explored in this term's organic chemistry class was the electrophilic substitution reaction. In this reaction, functional groups can be added onto the aromatic ring, leading to the formation of a substituted aromatic compound. One compound that is formed like this is nitrobenzene, which is formed through the electrophilic substitution reaction between nitric acid and benzene. Sulfuric acid is used as the reagent. Today, nitrobenzene is considered a poisonous organic compound that is commonly used in the production and manufacture of polishes and insulating compounds.

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ESTERIFICATION REACTION: ACETYLATION OF SALICYLIC ACID
One of the most commonly used pain killers used in the world is aspirin also known as acetyl salicylic acid. This drug serves as an pain reducer, fever reductant, and anti inflammatory agent. The formation of this popular drug is an acetylation reaction. In the reaction, an acetyl group is added to salicylic acid. The acetylaion reaction belongs to a group of reactions called esterfication. The ester of an acid, which in this reaction is acetic acid, is combined with salicylic acid. The reaction is catalyzed by an acid, which in this case is phosphoric acid.



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